Home Products Optoelectronic Tweezer System OptoBot®800 Series High-Throughput Single-Cell Optofluidic Sorting System
OptoBot®800 Series High-Throughput Single-Cell Optofluidic Sorting System

OptoBot®800 Series High-Throughput Single-Cell Optofluidic Sorting System

Optoelectronic Tweezer System
The system integrates optoelectronic tweezer (OET) technology with a fully automated microfluidic chip platform to deliver high-throughput cell screening, reducing labor and consumable costs while shortening experimental timelines from 2–3 months to 1–2 weeks.The system supports on-chip in situ culture together with two-well-plate incubation, enabling fully automated workflows from end to end. An intuitive graphical interface with configurable process steps makes custom assay design straightforward.
Product Features
  • Compatible with multiple OptoTrap Chip® formats
  • Automated sample loading/unloading with integrated sample needle washing
  • Fully automated on-board incubation, imaging, analysis, and optoelectronic tweezer (OET) operation
  • Full-chip optical imaging coverage with real-time image acquisition & storage
  • Automated optical calibration
  • Integrated operation and analysis software suite, including image processing and assay readout analytics
  • Onboard cell culture system accommodating one 96-well plate, with 4–40 °C temperature control and a 5% CO₂ atmosphere
  • Reagent bottle presence detection, automated reagent & sample level monitoring, and consumable replacement alerts
  • Automated needle clogging detection with system fault alerts
  • LED light source operating hours monitoring with replacement alerts
OptoBot®800 Series High-Throughput Single-Cell Optofluidic Sorting System


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Areas of Interest
Antibody Discovery
Cell and Gene Therapy (CGT)
Antibody Discovery
The process isolates single B cells and validates the function of their secreted antibodies to screen for high-specificity candidates. Subsequent sequencing and bioinformatics analysis align sequencing data with functional data, enabling the identification of specific antibody sequences.
Cell and Gene Therapy (CGT)
A high-throughput, automated workflow isolates target single cells from transient co-cultures for downstream analysis, enabling multidimensional characterization of T cell potency at single-cell resolution. Images captured during isolation allow for the tracking of specific cells or cell types.
Product Comparison


Configuration Comparison Table

Model

OptoBot® 1000 

OptoBot® 800

Appearance

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Product Positioning

 Fully Automated Full-size Integrated System  Benchtop System

Primary Applications

 Antibody Discovery、T-cell Characterization、Cell Line Development Antibody Discovery、T-cell Characterization

Hardware Design

Floor-standing / All-in-one Integrated System; Includes Integrated Touchscreen, PC, and Keyboard

Benchtop design; connects to an external workstation

Pneumatic Configuration

 GMP-compliant; Supports Positive Pressure (Express) or Negative Pressure (Standard/Plus) configurations GMP-compliant

Automated Incubation

 On-chip in situ incubation + two 96-well plates On-chip in situ incubation + one 96-well plate

Incubation Control

 Temperature: 10–50 °C (on-chip) / 4–40 °C (plate); 5% CO₂ Aligned with OptoBot® 1000

Optics & Imaging

5 Fluorescence Channels + Brightfield;
High-power LED Projection (1920×1080 DMD); 4.2MP CMOS Camera (100fps)

 Aligned with OptoBot® 1000

Objective Lenses

 Standard: 4X, 10X; Optional: 20X Aligned with OptoBot® 1000

Sample I/O

 1.5 mL Eppendorf (EP) tubes, 0.2 mL PCR tubes, standard 96-well microplates / PCR plates Aligned with OptoBot® 1000

Target Cell Types

 CHO cells, plasma B cells, memory B cells, T cells, hybridomas, primary cells, adherent cells, etc. Aligned with OptoBot® 1000